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When ionotropic receptors are activated, certain ion species such as Na to enter the postsynaptic neuron, which depolarizes the postsynaptic membrane.If more of the same type of postsynaptic receptors are activated, then more Na will enter the postsynaptic membrane and depolarize cell.An action potential can be divided into several sequential phases: threshold, rising phase, falling phase, undershoot phase, and recovery.

Ionotropic receptors are a combination of a receptor and an ion channel.Moreover, the distinctions based on function between neurons and other cells such as cardiac and muscle cells are not helpful.Thus, the fundamental difference between a neuron and a nonneuronal cell is a matter of degree.Plastic change often results from the alteration of the number of neurotransmitter receptors located on a synapse.There are several underlying mechanisms that cooperate to achieve synaptic plasticity, including changes in the quantity of neurotransmitters released into a synapse and changes in how effectively cells respond to those neurotransmitters.

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